Written by CalorieData Nutrition TeamReviewed by a Registered DietitianLast Updated: March 2026

Sub Sandwich vs Quesadilla: Nutrition Comparison

Which is healthier? Compare calories, protein, carbs, and more

Complete side-by-side nutrition comparison per 100g serving | Updated 2026

Which is Healthier?

Quesadilla is generally healthier

Quesadilla comes out ahead in this comparison, winning in 3 out of 5 key nutritional categories. It has fewer calories (255 vs 260), less sugar (1.8g vs 5.7g), less sodium (520mg vs 670mg)making it the better choice for most health goals.

Quick Summary

Fewer Calories

Quesadilla

255 kcal

More Protein

Sub Sandwich

12g

More Fiber

Sub Sandwich

2.4g

Less Sugar

Quesadilla

1.8g

Visual Comparison

Caloriesper 100g
Sub Sandwich
260
Quesadilla
255
Proteinper 100g
Sub Sandwich
12g
Quesadilla
12g
Carbohydratesper 100g
Sub Sandwich
38g
Quesadilla
20g
Fatper 100g
Sub Sandwich
5.8g
Quesadilla
14g

Side-by-Side Nutrition Table

NutrientSub SandwichQuesadillaDifference
Calories260kcal255kcal+5.0kcal
Protein12g12g0.0g
Carbohydrates38g20g+18.0g
Fat5.8g14g-8.2g
Fiber2.4g1.2g+1.2g
Sugar5.7g1.8g+3.9g
Sodium670mg520mg+150.0mg

Serving Size Comparison

All values above are per 100g. Here's how they compare in common serving sizes:

Sub Sandwich

Per 100g:260 calories
Per cup (150g):390 calories
Per serving (85g):221 calories

Quesadilla

Per 100g:255 calories
Per cup (150g):383 calories
Per serving (85g):217 calories

Diet Compatibility

Sub Sandwich

No specific diet tags

Quesadilla

No specific diet tags

When to Choose Sub Sandwich

  • Higher in protein (12g vs 12g)
  • More fiber (2.4g vs 1.2g)

Common Uses

Quick mealsDining outSocial eatingConvenience
View full Sub Sandwich nutrition →

When to Choose Quesadilla

  • Lower in calories (255 vs 260)
  • Lower in carbs (20g vs 38g)
  • Less sugar (1.8g vs 5.7g)
  • Lower sodium (520mg vs 670mg)

Common Uses

Quick mealsDining outSocial eatingConvenience
View full Quesadilla nutrition →

Sub Sandwich vs Quesadilla: Nutritional Analysis

Sub Sandwich is more calorie-dense at 260 calories per 100g compared to 255 for Quesadilla, a difference of 5 calories. These differences become meaningful when you consider how each food fits into your daily dietary pattern rather than looking at any single nutrient in isolation.

Macronutrient Breakdown

The macronutrient profiles of Sub Sandwich and Quesadilla tell different nutritional stories. Sub Sandwich provides 38g of carbohydrates, 5.8g of fat, and 2.4g of fiber per 100g, while Quesadilla contains 20g carbs, 14g fat, and 1.2g fiber. The higher fiber content in Sub Sandwich supports digestive health, helps regulate blood sugar after meals, and contributes to longer-lasting satiety. Sugar content also differs: Sub Sandwich contains 5.7g while Quesadilla has 1.8g per 100g. Lower sugar options are generally preferable for blood sugar management and dental health.

Key Takeaways

  • For weight management: Quesadilla is the lower-calorie choice at 255 cal/100g, making it more suitable for calorie-controlled diets.
  • For muscle building: Sub Sandwich provides more protein (12g/100g), supporting muscle repair and growth.
  • For sustained energy: Sub Sandwich offers more fiber (2.4g/100g), which slows digestion and provides steadier energy release.
  • Overall: Neither food is universally "better" than the other. The right choice depends on your specific nutritional goals, meal context, and dietary preferences. Both can play a role in a balanced diet.

Frequently Asked Questions

Which has more calories, Sub Sandwich or Quesadilla?

Sub Sandwich has more calories with 260 kcal per 100g, compared to Quesadilla with 255 kcal. That's a difference of 5 calories per 100g serving.

Is Sub Sandwich healthier than Quesadilla?

Based on our nutritional analysis, Quesadilla is generally the healthier choice, winning in 3 out of 5 key nutritional categories. Quesadilla has 255 calories, 12g protein, and 1.2g fiber per 100g. However, the best choice depends on your specific dietary goals.

What is the protein difference between Sub Sandwich and Quesadilla?

Sub Sandwich and Quesadilla have the same protein content at 12g per 100g.

Which is better for weight loss, Sub Sandwich or Quesadilla?

For weight loss, Quesadilla is the better choice with only 255 calories per 100g compared to 260 calories in Sub Sandwich. Sub Sandwich also offers 2.4g of fiber per 100g, which helps you feel fuller longer.

Does Sub Sandwich or Quesadilla have fewer carbs?

Quesadilla has fewer carbs with 20g per 100g, compared to Sub Sandwich with 38g. If you're following a low-carb diet, Quesadilla is the better option with 18.0g fewer carbohydrates.

About Our Data

All nutrition data in this comparison is sourced from the USDA FoodData Central, the official food composition database maintained by the U.S. Department of Agriculture. Values are based on 100g servings for accurate comparison.

Health Disclaimer: This comparison is for informational purposes only and is not intended as medical or dietary advice. Nutritional needs vary by individual. The best food choice depends on your personal health goals, dietary requirements, and preferences. Consult a healthcare provider or registered dietitian for personalized nutrition guidance.